Ethyl Alcohol vs. Isopropyl Alcohol: Uses and Effectiveness (2024)

Ethyl Alcohol vs. Isopropyl Alcohol: Uses and Effectiveness (1)Share on Pinterest

Ethyl and isopropyl alcohol are both used as disinfectants and antiseptics and can be effective at killing germs. Ethyl alcohol may cause less skin damage.

If you look at the back of your bottle of hand sanitizer, you’ll likely see ethyl or isopropyl alcohol listed in the ingredients.

Both types of alcohol can be effective at killing germs and are used in healthcare as disinfectants and antiseptics. Studies have found that both alcohols are most effective at killing germs when they’re diluted with water to about 70 percent.

When buying a hand sanitizer, you should check the label to make sure it contains a minimum of 60 percent of either type of alcohol. You may also see ethyl alcohol listed as ethanol or simply “alcohol.”

Isopropyl alcohol can also appear as “2-propanol” on labels.

Keep reading to learn how ethyl and isopropyl alcohol differ and which one is more effective.

Ethyl and isopropyl alcohol are similar molecularly but have different chemical structures.

In chemistry, the definition of alcohol is an organic molecule that contains a hydroxyl group bonded to a saturated carbon atom. A hydroxyl group is an oxygen molecule bonded with hydrogen, written as -OH.

Ethyl alcohol

Ethyl alcohol, also known as ethanol, is the most well-known alcohol. It’s the type of alcohol people consume in alcoholic beverages. The chemical structure of ethanol is C2H5OH.

Ethyl alcohol is naturally produced by yeasts when they ferment sugars. As well as being consumed in beverages, it’s used medically as an antiseptic and disinfectant.

Ethyl alcohol is a common addition to motor fuels. More than 98 percent of gasoline in the United States contains ethyl alcohol.

Isopropyl alcohol

Isopropyl alcohol is also commonly called “rubbing alcohol.” Its molecular structure contains one more carbon and two more hydrogen molecules than ethyl alcohol. Its formula is written as C3H7OH.

Like ethanol, it’s commonly used as an antiseptic and disinfectant. It’s also found in lotions, cosmetics, and face washes.

Ingesting hand sanitizers can lead to death

Consuming hand sanitizers and other alcohol products not made for consumption can lead to serious health consequences or death, even if the label says “ethyl alcohol.” Hand sanitizers made outside the United States can contain another highly toxic alcohol called methanol.

The Centers for Disease Control and Prevention (CDC) reported 15 cases of methanol poisoning associated with drinking alcohol-based hand sanitizers from May 1 to June 30, 2020. Four of the people died and three had permanent vision loss.

Even drinking small amounts of isopropyl alcohol is poisonous to children. Coma, seizures, and dangerously low blood sugar are some of the possible side effects.

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The CDC recommends choosing a hand sanitizer that contains at least 60 percent ethyl or isopropanol alcohol and avoiding products that contain less than 60 percent. Both types of alcohol can kill bacteria, viruses, and other germs that can make you sick.

Ethyl alcohol is effective at killing a large range of viruses, but this doesn’t include hepatitis A or poliovirus.

Isopropyl alcohol isn’t as effective against a class of viruses called nonenveloped viruses but is effective at killing enveloped viruses.

The virus that causes COVID-19 is an enveloped virus. Both types of alcohol are effective at killing it, but ethyl may be more effective.

Ethyl vs. isopropyl alcohol for skin health

A 2017 study compared the effects of three types of alcohol on skin health. The researchers found that isopropyl alcohol and n-propanol caused significant damage to skin condition and function, but ethyl alcohol didn’t.

They concluded that ethanol is the best alcohol to apply to your skin, especially if you use it frequently.

Should you use ethyl or isopropyl alcohol for babies and children?

Hand sanitizers containing isopropyl, or ethyl alcohol aren’t dangerous for children or babies when used correctly. But drinking even small amounts can lead to alcohol poisoning, so the FDA recommends only giving them to children under 6 with adult supervision.

The FDA also notes that there’s no need to be concerned if your child licks their hands or eats with their hands after applying hand sanitizer.

According to the World Health Organization (WHO), ethyl is generally considered superior to isopropyl alcohol, but both types of alcohol are effective at killing flu and cold viruses.

A 2021 study published in The Journal of Hospital Infection found that isopropyl or ethyl alcohol in concentrations of 62 to 80 percent was very efficient at disinfecting surfaces from the virus that causes COVID-19.

Ethyl alcohol is safe for consumption in small amounts when it’s consumed in alcoholic beverages. But alcohol is linked to numerous negative health effects and over-consuming ethyl can lead to alcohol poisoning.

Drinking isopropyl alcohol is extremely dangerous and can easily lead to alcohol poisoning. It’s about twice as potent as ethyl alcohol. It’s estimated that about 250 milliliters (8.5 fluid ounces) is lethal to humans. In some cases, as little as 100 milliliters (3.4 fluid ounces) can be fatal.

A concentration of about 70 percent isopropanol or ethyl alcohol is most effective for killing germs.

In general, solutions with 60 to 90 percent alcohol tend to be more effective at killing viruses than solutions with alcohol concentrations outside this range. Weaker concentrations are noticeably less effective because less alcohol comes into contact with germs.

Stronger concentrations may be less effective because there’s not enough water. Water is needed to increase contact time with viruses and slow down evaporation.

Alcohol destroys germs by breaking down fats and proteins that they need to survive.

The exact mechanism of isopropyl alcohol’s ability to break down germs isn’t known, but it’s thought to break down proteins and the DNA that viruses, bacteria, and other germs need to survive. It’s also thought to dissolve the fat and protein that make up their protective outer membrane.

Ethanol kills germs in a similar way, by breaking down their essential fats and proteins they need to survive.

Ethyl alcohol and isopropyl alcohol are commonly used as disinfectants and antiseptics. Both alcohols are effective at killing germs when used in concentrations over 60 percent, but there’s some evidence that ethyl alcohol is less damaging to your skin.

It’s extremely dangerous to drink products containing either type of alcohol that aren’t meant for human consumption. If your child drinks hand sanitizer, you should seek immediate medical attention.

Ethyl Alcohol vs. Isopropyl Alcohol: Uses and Effectiveness (2024)

FAQs

Ethyl Alcohol vs. Isopropyl Alcohol: Uses and Effectiveness? ›

Ethyl alcohol is effective at killing a large range of viruses, but this doesn't include hepatitis A or poliovirus . Isopropyl alcohol isn't as effective against a class of viruses called nonenveloped viruses but is effective at killing enveloped viruses.

Which is more effective, isopropyl or ethyl alcohol? ›

Isopropyl alcohol is effective against viruses such as FCV at 40% – 60% concentrations. Ethanol however, is more effective at 70% – 90% concentrations against FCV. Contact time indicates how effective an alcohol is against a target microbe in a given period of time.

Why is isopropyl alcohol used instead of ethanol? ›

The vital difference between isopropyl alcohol and ethyl alcohol is that the latter is safe for human consumption, while the former is hazardous for ingestion. However, denaturants added to ethanol in industrial disinfecting and cleaning products make it unpalatable for consumption.

Why is it better to use 70% isopropyl alcohol than 100% ethanol to use as a disinfectant? ›

70% IPA solutions penetrate the cell wall more completely which permeates the entire cell, coagulates all proteins, and therefore the microorganism dies. Extra water content slows evaporation, therefore increasing surface contact time and enhancing effectiveness.

Is isopropanol or ethanol better for cleaning? ›

Ethanol is commonly used in surface cleaning areas whereas isopropyl alcohol can be used as an antiseptic which is used in most hospitals. They are effective at 70% concentration and are used to clean tools after they are immersed for 10 minutes. Moreover, they evaporate quickly and don't leave a residue behind.

Can I use ethyl alcohol to clean electronics? ›

For cleaning electronics you should only use ultra-pure electronics grade ethanol, which is completely mineral-free and contains (almost) no water. Ethyl alcohol is not a particularly strong solution, but it is relatively inexpensive and ideal for such routine tasks as removing layers of accumulated dirt or corrosion.

Can I mix isopropyl and ethyl alcohol? ›

It is not bad to mix ethyl and isopropyl alcohols. They do not react with each other. They both disinfect.

What is the best alcohol for cleaning? ›

You can buy rubbing alcohol with a concentration of 70% or 99% isopropyl alcohol. Even though you may think the higher concentration is more effective, experts say 70% is actually better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria.

When not to use IPA? ›

IPA is not effective on mineral oils and most hand lotions. IPA simply does not have the cleaning “muscle” to remove oils and greases very well. Drying-speed is another issue with IPA. Slow-drying IPA can be trapped inside a fiber optic connector.

Which alcohol is best for cleaning electronics? ›

For electronic printed circuit board (PCB) assembly, you will find isopropyl alcohol being used either to clean flux residues from recently soldered circuit boards, or in PCB repair and rework.

Why is 100% ethanol not used? ›

Here, if the ethanol concentration were too high (100%), the pellet could dry out too much, making it difficult to be re-suspended. Also, as I said before, high concentrations of ethanol facilitate the precipitation of contaminants, and we don't want that!

What are the uses of ethyl alcohol? ›

It is used as a topical agent to prevent skin infections, in pharmaceutical preparations (e.g. rubbing compounds, lotions, tonics, colognes), cosmetics, and in perfumes.

Is isopropyl alcohol the same as nail polish remover? ›

According to Boyce, rubbing alcohol or hand sanitizer are two of the best ways to remove polish without needing an acetone remover. "Apply some to a cotton ball or pad and place it on your nail," Boyce says. "Let it sit for about 10 seconds and gently rub it back-and-forth.

Why is ethyl better than isopropyl? ›

Ethyl alcohol is effective at killing a large range of viruses, but this doesn't include hepatitis A or poliovirus . Isopropyl alcohol isn't as effective against a class of viruses called nonenveloped viruses but is effective at killing enveloped viruses.

Is everclear just rubbing alcohol? ›

Everclear is a brand name of rectified spirit (also known as grain alcohol and neutral spirit) produced by the American company Luxco (formerly known as the David Sherman Corporation, and since 2021 a subsidiary of MGP Ingredients).

What is the alcohol that is most effective as a disinfectant? ›

Ethyl alcohol (70%) is a powerful broad-spectrum germicide and is considered generally superior to isopropyl alcohol.

What concentration of alcohol is most effective as a disinfectant? ›

You can buy rubbing alcohol with a concentration of 70% or 99% isopropyl alcohol. Even though you may think the higher concentration is more effective, experts say 70% is actually better for disinfecting. It has more water, which helps it to dissolve more slowly, penetrate cells, and kill bacteria.

Which alcohol is the best disinfectant? ›

Ethyl alcohol (70%) is a powerful broad-spectrum germicide and is considered generally superior to isopropyl alcohol.

Is ethanol or isopropyl alcohol better for extraction? ›

Isopropyl alcohol is more suitable for low-yield extractions, while ethanol is more suitable for high-yield extractions.

What is better 70% or 99% isopropyl alcohol? ›

Better for Cleaning Surfaces: The slower evaporation rate of a 70% solution makes it more suitable for cleaning surfaces. It stays on surfaces longer than a 99% solution, ensuring thorough cleaning and disinfection. Cost-Effectiveness: Diluting 99% isopropyl alcohol to make a 70% solution can be more cost-effective.

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